Conduct large scale systematic literature reviews to consolidate all available published and unpublished data at global level to inform RSV burden in pregnant women and infants, and synthesise evidence to inform development of severity scores for RSV infection.
Model the impact of COVID-19 on health-care utilisation for RSV using national and regional routine healthcare data.
Evaluate the impact of COVID-19 on RSV seasonality.
Model the cost-effectiveness of RSV vaccination in older adults aged 65 years post COVID-19.
Identify mucosal correlates for disease severity in paediatric RSV infection and validate correlates identified from peripheral blood in samples from the respiratory site of disease.
Confirm the most relevant RESCEU biomarkers associated with RSV infection susceptibility by performing functional analyses of the respiratory and gut microbiomes in order to identify potential underlying mechanisms and translate this scientific knowledge into concrete applications for RSV patients.
Build upon RESCEU data by confirming the suitability of RSV-specific serum IgA as a biomarker of prior wild type (WT) RSV experience in infants and further investigate interference by maternal antibodies.
Coordinate and steer all project activities, promoting strategic direction, alignment and achievement of the project goals.
Set-up a project management structure that ensures efficient operational execution of the project, including administrative support, financial allocation/reporting, legal issues, and organisation of project meetings.
Ensure project implementation according to the work plan, including timely delivery of results, link and workflow between WPs, with an adequate quality level and within cost, including risk management and quality control procedures on deliverables.
Promote effective internal communication and knowledge management and work dynamics between participants.
Developdata visualisation solutions of the outputs generated in PROMISE to ensure awareness and sustainability of the assets for the for the global community.
Develop an external communication plan to disseminate and promote PROMISE results to external stakeholders, including data visualisation solutions.
Provide an efficient plan and foresight to guarantee the project sustainability.
Coordinate and ensure the correct strategic alignment between the RESCEU and PROMISE projects, including ethical oversight and Public Private Partnership (PPP) governance.
Ensure compliance with the ethics requirements set out for the project.
This project has received funding from the Innovative Medicines Initiative 2 Joint Undertaking under grant agreement 101034339. This Joint Undertaking receives support from the European Union’s Horizon 2020 research and innovation programme and EFPIA.
The Innovative Medicines Initiative is a partnership between the European Union and the European pharmaceutical industry, represented by the European Federation of Pharmaceutical Industries and Associations (EFPIA). It is working to improve health by speeding up the development of the next generation of medicines, particularly in areas where there is an unmet medical or social need. It works by facilitating collaboration between the key players involved in health research, including universities, research centres, the pharmaceutical and other industries, small and medium-sized enterprises (SMEs), patient organisations, and medicines regulators. IMI is the world’s biggest public-private partnership (PPP) in the life sciences.
Collect information about user navigation through the site in order to know the origin of the visits and other similar data at a statistical level.