Main author:


Work Package:

WP2 – Preparation for future RSV product assessment

PDF file

Using similar endpoints in clinical RSV studies (both clinical trials and observational studies) is crucial for the comparability of the efficacy or effectiveness of different products. Furthermore, the use of standardized endpoints helps determine the comparative cost-effectiveness of interventions in the society. We have reviewed endpoints used in previous clinical studies in the field of RSV and influenza and the strengths and limitations of each endpoint. This document is intended as a starting point for discussions between public health and private stakeholders and will feed into later PROMISE outputs, including study protocols. Future work (backed by a full systematic review of endpoints used in literature and stakeholder consultation) could classify endpoints further e.g., based on specificity and clinical relevance as well as pragmaticism and cost-efficiency of studying them.

Published On: June 6, 2023